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1.
Healthcare (Basel) ; 11(20)2023 Oct 18.
Artigo em Inglês | MEDLINE | ID: mdl-37893836

RESUMO

Alzheimer's disease is a common neurological disorder and mental disability that causes memory loss and cognitive decline, presenting a major challenge to public health due to its impact on millions of individuals worldwide. It is crucial to diagnose and treat Alzheimer's in a timely manner to improve the quality of life of both patients and caregivers. In the recent past, machine learning techniques have showed potential in detecting Alzheimer's disease by examining neuroimaging data, especially Magnetic Resonance Imaging (MRI). This research proposes an attention-based mechanism that employs the vision transformer approach to detect Alzheimer's using MRI images. The presented technique applies preprocessing to the MRI images and forwards them to a vision transformer network for classification. This network is trained on the publicly available Kaggle dataset, and it illustrated impressive results with an accuracy of 99.06%, precision of 99.06%, recall of 99.14%, and F1-score of 99.1%. Furthermore, a comparative study is also conducted to evaluate the performance of the proposed method against various state-of-the-art techniques on diverse datasets. The proposed method demonstrated superior performance, outperforming other published methods when applied to the Kaggle dataset.

2.
Healthcare (Basel) ; 11(19)2023 Sep 29.
Artigo em Inglês | MEDLINE | ID: mdl-37830690

RESUMO

Motor imagery, an intricate cognitive procedure encompassing the mental simulation of motor actions, has surfaced as a potent strategy within the neuro-rehabilitation domain. It presents a non-invasive, economically viable method for facilitating individuals with disabilities in enhancing their motor functionality and regaining self-sufficiency. This manuscript delivers an exhaustive analysis of the significance of motor imagery in augmenting functional rehabilitation for individuals afflicted with physical impairments. It investigates the fundamental mechanisms governing motor imagery, its applications across diverse disability conditions, and the prospective advantages it renders. Moreover, this document addresses the prevailing obstacles and prospective trajectories in this sector, accentuating the necessity for continued investigation and the invention of cutting-edge technologies that optimize the potentiality of motor imagery in aiding disabled persons.

3.
Diagnostics (Basel) ; 13(8)2023 Apr 21.
Artigo em Inglês | MEDLINE | ID: mdl-37189603

RESUMO

Monkeypox (MPX) is a disease caused by monkeypox virus (MPXV). It is a contagious disease and has associated symptoms of skin lesions, rashes, fever, and respiratory distress lymph swelling along with numerous neurological distresses. This can be a deadly disease, and the latest outbreak of it has shown its spread to Europe, Australia, the United States, and Africa. Typically, diagnosis of MPX is performed through PCR, by taking a sample of the skin lesion. This procedure is risky for medical staff, as during sample collection, transmission and testing, they can be exposed to MPXV, and this infectious disease can be transferred to medical staff. In the current era, cutting-edge technologies such as IoT and artificial intelligence (AI) have made the diagnostics process smart and secure. IoT devices such as wearables and sensors permit seamless data collection while AI techniques utilize the data in disease diagnosis. Keeping in view the importance of these cutting-edge technologies, this paper presents a non-invasive, non-contact, computer-vision-based method for diagnosis of MPX by analyzing skin lesion images that are more smart and secure compared to traditional methods of diagnosis. The proposed methodology employs deep learning techniques to classify skin lesions as MPXV positive or not. Two datasets, the Kaggle Monkeypox Skin Lesion Dataset (MSLD) and the Monkeypox Skin Image Dataset (MSID), are used for evaluating the proposed methodology. The results on multiple deep learning models were evaluated using sensitivity, specificity and balanced accuracy. The proposed method has yielded highly promising results, demonstrating its potential for wide-scale deployment in detecting monkeypox. This smart and cost-effective solution can be effectively utilized in underprivileged areas where laboratory infrastructure may be lacking.

4.
World J Clin Cases ; 11(1): 84-91, 2023 Jan 06.
Artigo em Inglês | MEDLINE | ID: mdl-36687200

RESUMO

Diabetic wound takes longer time to heal due to micro and macro-vascular ailment. This longer healing time can lead to infections and other health complications. Foot ulcers are one of the most common diabetic wounds. These are one of the leading cause of amputations. Medical science is continuously striving for improving quality of human life. A recent trend of amalgamation of knowledge, efforts and technological advancement of medical science experts and artificial intelligence researchers, has made tremendous success in diagnosis, prognosis and treatment of a variety of diseases. Diabetic wounds are no exception, as artificial intelligence experts are putting their research efforts to apply latest technological advancements in the field to help medical care personnel to deal with diabetic wounds in more effective manner. The presented study reviews the diagnostic and treatment research under the umbrella of Artificial Intelligence and computational science, for diabetic wound healing. Framework for diabetic wound assessment using artificial intelligence is presented. Moreover, this review is focused on existing and potential contribution of artificial intelligence to improve medical services for diabetic wound patients. The article also discusses the future directions for the betterment of the field that can lead to facilitate both, clinician and patients.

5.
Biomed Tech (Berl) ; 64(3): 297-307, 2019 May 27.
Artigo em Inglês | MEDLINE | ID: mdl-30055096

RESUMO

Diabetes mellitus is an enduring disease related with significant morbidity and mortality. The main pathogenesis behind this disease is its numerous micro- and macrovascular complications. In developing countries, diabetic retinopathy (DR) is one of the major sources of vision impairment in working age population. DR has been classified into two categories: proliferative diabetic retinopathy (PDR) and non-proliferative diabetic retinopathy (NPDR). NPDR is further classified into mild, moderate and severe, while PDR is further classified into early PDR, high risk PDR and advanced diabetic eye disease. DR is a disease caused due to high blood glucose levels which result in vision loss or permanent blindness. High-level advancements in the field of bio-medical image processing have speeded up the automated process of disease diagnoses and analysis. Much research has been conducted and computerized systems have been designed to detect and analyze retinal diseases through image processing. Similarly, a number of algorithms have been designed to detect and grade DR by analyzing different symptoms including microaneurysms, soft exudates, hard exudates, cotton wool spots, fibrotic bands, neovascularization on disc (NVD), neovascularization elsewhere (NVE), hemorrhages and tractional bands. The visual examination of the retina is a vital test to diagnose DR-related complications. However, all the DR computer-aided diagnostic systems require a standard dataset for the estimation of their efficiency, performance and accuracy. This research presents a benchmark for the evaluation of computer-based DR diagnostic systems. The existing DR benchmarks are small in size and do not cover all the DR stages and categories. The dataset contains 1445 high-quality fundus photographs of retinal images, acquired over 2 years from the records of the patients who presented to the Department of Ophthalmology, Holy Family Hospital, Rawalpindi. This benchmark provides an evaluation platform for medical image analysis researchers. Furthermore, it provides evaluation data for all the stages of DR.


Assuntos
Retinopatia Diabética/patologia , Processamento de Imagem Assistida por Computador/métodos , Edema Macular/fisiopatologia , Retina/fisiopatologia , Algoritmos , Benchmarking , Exsudatos e Transudatos , Fundo de Olho , Humanos
6.
Technol Cancer Res Treat ; 17: 1533033818802789, 2018 01 01.
Artigo em Inglês | MEDLINE | ID: mdl-30261827

RESUMO

Leukemia is a fatal disease of white blood cells which affects the blood and bone marrow in human body. We deployed deep convolutional neural network for automated detection of acute lymphoblastic leukemia and classification of its subtypes into 4 classes, that is, L1, L2, L3, and Normal which were mostly neglected in previous literature. In contrary to the training from scratch, we deployed pretrained AlexNet which was fine-tuned on our data set. Last layers of the pretrained network were replaced with new layers which can classify the input images into 4 classes. To reduce overtraining, data augmentation technique was used. We also compared the data sets with different color models to check the performance over different color images. For acute lymphoblastic leukemia detection, we achieved a sensitivity of 100%, specificity of 98.11%, and accuracy of 99.50%; and for acute lymphoblastic leukemia subtype classification the sensitivity was 96.74%, specificity was 99.03%, and accuracy was 96.06%. Unlike the standard methods, our proposed method was able to achieve high accuracy without any need of microscopic image segmentation.


Assuntos
Processamento de Imagem Assistida por Computador/métodos , Leucemia-Linfoma Linfoblástico de Células Precursoras/classificação , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico por imagem , Humanos , Redes Neurais de Computação , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia
7.
Comput Math Methods Med ; 2018: 6125289, 2018.
Artigo em Inglês | MEDLINE | ID: mdl-29681996

RESUMO

Leukaemia is a form of blood cancer which affects the white blood cells and damages the bone marrow. Usually complete blood count (CBC) and bone marrow aspiration are used to diagnose the acute lymphoblastic leukaemia. It can be a fatal disease if not diagnosed at the earlier stage. In practice, manual microscopic evaluation of stained sample slide is used for diagnosis of leukaemia. But manual diagnostic methods are time-consuming, less accurate, and prone to errors due to various human factors like stress, fatigue, and so forth. Therefore, different automated systems have been proposed to wrestle the glitches in the manual diagnostic methods. In recent past, some computer-aided leukaemia diagnosis methods are presented. These automated systems are fast, reliable, and accurate as compared to manual diagnosis methods. This paper presents review of computer-aided diagnosis systems regarding their methodologies that include enhancement, segmentation, feature extraction, classification, and accuracy.


Assuntos
Diagnóstico por Computador/métodos , Leucemia-Linfoma Linfoblástico de Células Precursoras/diagnóstico , Algoritmos , Teorema de Bayes , Análise por Conglomerados , Biologia Computacional , Diagnóstico por Computador/estatística & dados numéricos , Fractais , Lógica Fuzzy , Humanos , Interpretação de Imagem Assistida por Computador/métodos , Linfócitos/patologia , Modelos Estatísticos , Redes Neurais de Computação , Reconhecimento Automatizado de Padrão , Leucemia-Linfoma Linfoblástico de Células Precursoras/sangue , Leucemia-Linfoma Linfoblástico de Células Precursoras/patologia , Máquina de Vetores de Suporte
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